Development of an Artificial Intelligence Model in Lung Cancer Screening for the Diagnosis of Lung Nodules and Risk Stratification in Subjects With Occupational and/or Smoking Exposure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 728
- 试验地点
- 1
- 主要终点
- AIM 1 Pilot deep learning model
研究概览
简要总结
Single-center, non-profit, observational, retrospective study of collection of clinical and amnestic data and images to create, implement and develop a pilot model of an integrated virtual platform.
详细描述
The project we propose is a study whose objective was to develop an artificial intelligence program integrated into a web-based platform for the optimization of the performance of lung cancer screening for the diagnosis of lung nodules and risk stratification in subjects exposed to environmental carcinogens and/or cigarette smoke.
Inclusion criteria:
Age > 50; smokers for at least 20 pack-years (20 cigarillos a day for 20 years) or former heavy smokers if they quit less than 15 years ago; and/or previous professional exposure to asbestos; absence of lung cancer symptoms; who performed lung cancer screening after the year 2000 upon approval of the study by the relevant EC.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age > 50 years;
- •smokers for at least 20 pack-years (20 cigarettes a day for 20 years) or former heavy smokers if they quit less than 15 years ago;
- •and/or previous professional exposure to asbestos;
- •absence of lung cancer symptoms;
- •who performed lung cancer screening after the year 2000 upon approval of the study by the relevant Etical Committee
排除标准
- •Age < 50 years
- •never smokers
- •lung cancer symptoms
结局指标
主要结局
AIM 1 Pilot deep learning model
时间窗: from enrollment to the end of treatment at 2 years
Development and fine-tuning of a pilot deep learning model for automatic detection and diagnosis of screen-detected nodules for risk stratification in subjects with asbestos exposure as part of a lung cancer screening program in high-risk subjects for exposure to asbestos and smoking on retrospective data.
次要结局
- AIM 2 Clinical database(from enrollment to the end of treatment at 2 years)
研究者
Giulia Veronesi
Medical Doctor
Scientific Institute San Raffaele