NCT03484260已完成不适用
Association Between the Prevalence of Cardiovascular Risk Factors and New Use of Testosterone
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Bayer
- 入组人数
- 27,778
- 试验地点
- 1
- 主要终点
- Estimation of the association between cardiovascular risk factors and initiation of testosterone therapy
研究概览
简要总结
We will investigate if testosterone is preferentially given to patients at higher risk of cardiovascular events. If this is the case, then observational studies may be prone to selection bias resulting in overestimation of the cardiovascular risk associated with testosterone when compared to a healthier population not taking testosterone
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •All male individuals in the source population with a first testosterone use during the study period will be included as cases. The date of the GP consultation associated with the first testosterone prescription will be designated as the index day.
排除标准
- •Patients of less than 18 years on the index day, with less than 2-year contribution to the CPRD-HES link before the index day, or with use of testosterone before the study period will be excluded from the group of cases.
研究组 & 干预措施
Case group: Testosterone Product
Male subjects prescribed testosterone in UK
干预措施: Testosterone Product (Drug)
结局指标
主要结局
Estimation of the association between cardiovascular risk factors and initiation of testosterone therapy
时间窗: Retrospectively from 01 January 2001 to 31 March 2016
次要结局
未报告次要终点
研究者
研究点 (1)
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