Improving Aspirin Prescription Rates in Outpatient Clinic

Recruiting

• Conditions: Low Birth Weight; Small for Gestational Age (SGA); Preeclampsia (PE); Prevention &Amp; Control
• Interventions: Other: Aspirin prescription on outpatient basis

• Registration Number: NCT06694233
• Lead Sponsor: Cairo University

Brief Summary

Ρrееςlаmpѕia is a syndrome characterised by the new onset of hуреrtеnѕion plus proteinuria, end-organ dysfunction, or both after 20 weeks of gestation. It complicates 3-5% of pregnancies.

Low-dose aspirin reduces the frequency of рrееςlampsia, as well as related adverse рrеgոaոcy outcomes (preterm birth, growth restriction), by 10 to 70% when taken by patients аt moderate to high risk of the disease. It has an excellent maternal/fetal safety profile. Thus, it is a reasonable preventive strategy for these patients.

A pilot study at our hospital found that not all patients who are candidates for aspirin prescription receive it (only 40%). This audit cycle aims to increase aspirin prescription rates for moderate and high-risk obstetric populations.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-11-01
• Study First Submitted: 2024-11-14
• Study First Submitted QC: 2024-11-15
• Study First Posted: 2024-11-19
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-02
• Last Update Posted: 2024-12-04
• Primary Completion: 2025-04-30
• Study Completion: 2025-04-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 300

Inclusion Criteria

Women at high risk are those with any of the following:

1. hypertensive disease during a previous pregnancy
2. chronic kidney disease
3. autoimmune disease such as systemic lupus erythematosus or antiphospholipid syndrome
4. type 1 or type 2 diabetes
5. chronic hypertension.

Women with more than one moderate risk factor, such as are:

1. nulliparity
2. age 40 years or older
3. pregnancy interval of more than 10 years
4. body mass index (BMI) of 35 kg/m2 or more at first visit
5. family history of pre-eclampsia
6. multi-fetal pregnancy.

Exclusion Criteria

• None. All eligible candidates will be included.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Obstetric population candidate for aspirin prescription	Aspirin prescription on outpatient basis	Moderate- and high-risk obstetric population

Primary Outcome Measures

Name	Time	Method
Aspirin prescription	Six months

Trial Locations

Locations (1)

Adan hospital; 🇰🇼 Hadiya, Ahmadi, Kuwait