A study to determine serum periostin levels over a six month period in adult patients, following a short or long bone fracture, or undergoing hip or knee joint replacement, or open reduction internal fixation surgery

Medical Research Institute of New Zealand0 个研究点目标入组 102 人开始时间: 2014年2月7日最近更新: 2020年1月13日

适应症

试验速览

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•Aged between 18 to 75 years
•Able to provide informed consent
•Experienced a fracture to short or long bone less than 48 hours prior, or undergoing hip or knee joint replacement, or or open reduction internal fixation (ORIF) surgery
•Participants will be enrolled to the following groups:
•34 participants with a short-bone or phalangeal fracture
•34 participants with a long bone fracture
•34 participants undergoing hip or knee joint replacement surgery, or open reduction internal fixation (ORIF) surgery

•Doctor’s diagnosis of Asthma, Bronchitis or COPD
•Wheezing or use of respiratory inhalers in the past 12 months
•Known pregnancy
•Significant co morbidities (determined at investigator discretion)
•Hospital admission within last 3 months
•Surgery within last 3 months, determined at investigator discretion (this includes all major surgery requiring general anaesthetic, dental extractions and root canal procedures. This does not include minor procedures, including but not limited to mole or wart removal, dental fillings etc).
•Systemic Corticosteroids within the last 3 months
•Any other safety concern at the investigator’s discretion

发起方