CLE and OCT in acute respiratory insufficiency

Completed

• Conditions: Non-resolving acute respiratory insufficiency in mechanically ventilated patients; 10024967

• Registration Number: NL-OMON47517
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

- *18 years of age
- Admitted to the intensive care unit of the Academic Medical Center
- Non-resolving acute respiratory failure mandating a standard diagnostic bronchoscopy with broncho-alveolar lavage

Exclusion Criteria

- Inability and willingness to provide informed consent by family-members
- Inability to comply with the study protocol

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- Assessing technical feasibility of pCLE and OCT of various<br /><br>(diseased/non-diseased on HR-CT-scan) alveolar compartments in mechanically<br /><br>ventilated patients. (% of successful videos/time for procedure (min))<br /><br><br /><br>- Assessing procedure-related adverse events of pCLE and OCT </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>- To compare the pCLE/OCT imaging with the radiological patterns<br /><br><br /><br>- To compare the pCLE/OCT-imaging with the histopathology (where available)</p><br>