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Developing Non-Communicable Disease Registries in Africa : A Step Towards Providing Quality Data for Improving Patient Outcomes

Conditions
Non-Communicable Disease
Registration Number
NCT03473795
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Brief Summary

This umbrella protocol seeks to develop robust data registries for non-communicable diseases (NCDs) in sub-Saharan Africa (SSA) with the aim of providing accurate and comprehensive data for the evaluation of such diseases in sub-Saharan African countries.Healthy volunteers will be included in the study for comparison.

Additionally, the investigators aim to describe the gut microbiome community diversity of a cohort of community dwelling Nigerians and compare with CRC patients in Nigerian and at MSK. We will collect stool for microbiome and metabolomic analysis from community dwelling persons in the catchment area of ARGO facilities in Nigeria while contemporaneously administering an extensive medical and environmental exposure questionnaire.

Detailed Description

Not available

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
10000
Inclusion Criteria
  • Age 18 and older.
  • Suspected or confirmed diagnosis of a non-communicable disease. OR
  • Healthy volunteers/no confirmed diagnosis for comparison.
Exclusion Criteria
  • Participants unwilling to sign consent.
  • Participants under the age of 18

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
# of patients that develope non-communicable diseases in Africa5 years
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (12)

Memorial Sloan Kettering Cancer Center

🇺🇸

New York, New York, United States

National Hospital of Abuja (Data collection only)

🇳🇬

Abuja, Central Business District, Nigeria

Lagos State University Teaching Hospital

🇳🇬

Ikeja, Nigeria

Olabisis Onabanjo University Teaching Hospital

🇳🇬

Sagamu, Ogun State, Nigeria

Federal Medical Centre Owo

🇳🇬

Owo, Nigeria

University College Hospital

🇳🇬

Ibadan, Oyo, Nigeria

Ladoke Akintola University of Technology

🇳🇬

Ogbomoso, Oyo, Nigeria

University Of Nigeria Teaching Hospital (UNTH) Ituku-Ozalla Enugu

🇳🇬

Enugu, Nigeria

Obafemi Awolowo University Teaching Hospitals Complex (OAUTHC)

🇳🇬

Ile-Ife, Nigeria

University of Ilorin Teaching Hospitals

🇳🇬

Ilorin, Nigeria

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Memorial Sloan Kettering Cancer Center
🇺🇸New York, New York, United States

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