Recurrent respiratory tract infections (RRTI) in the elderly: from phenotypic and immunological characterizaton to a mechanistic unravelling of a potential primary immunodeficiency (PID).

Completed

• Conditions: humoral deficiency; antibody immune defect; 10021429; 10004018; 10024970

• Registration Number: NL-OMON42241
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

- > 45 years old
AND
- two or more documented invasive bacterial or viral sino-, and/or pulmonary infections over the previous year
- no RRTI in early adulthood, adolescence or childhood
AND/OR
- an atypical microbial aetiology, an atypical course of infection or a belated response or early relapse on antibiotic treatments

Exclusion Criteria

- secundary immunodeficiency (for example HIV, immunesuppresiva, malignancy)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified