Proton pump inhibitors, oral and injectable, in preventing peptic ulcer re-bleeding
Not Applicable
- Conditions
- gastroduodenal ulcer.Peptic ulcer, site unspecified
- Registration Number
- IRCT2014082515510N2
- Lead Sponsor
- Vice Chancellor for research of Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 260
Inclusion Criteria
Inclusion Criteria: Every person with upper gastrointestinal bleeding due to peptic ulcer, which is the new log endoscopic bleeding (bleeding ulcer in the jet, the vessel featured in the wound bed, the wound with mild persistent bleeding, and ulcers with adherent clots in bed ).
Exclusion criteria: patients with upper GI bleeding with other causes, such as bleeding from esophageal or gastric varices or cancer and patients with clean base peptic ulcer without active bleeding.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endoscopic evidence of bleeding from gastric or duodenal ulcer. Timepoint: ?Before intervention, 72 hours an 4 weeks after intervention. Method of measurement: Endoscopy before intervention, check of blood pressureand hemoglobin 72 hours and 4 weeks after intervention.
- Secondary Outcome Measures
Name Time Method The number of units of blood required. Timepoint: 8 weeks after intervention. Method of measurement: Questionnaire.;Need for surgery. Timepoint: Upto 4 weeks after intervention. Method of measurement: Questionnaire.;Days of hospitalization. Timepoint: Upto 4 weeks after intervention. Method of measurement: Questionnaire.;The need for re-endoscopy because of bleeding. Timepoint: Upto 4 weeks after intervention. Method of measurement: Questionnaire.