An uncontrolled trial comparing the effects of sleep restriction and alcohol on driving simulator performance in obstructive sleep apnoea (OSA) patients versus matched controls and evaluating the effectiveness of continuous positive air-way pressure (CPAP) treatment in improving driving simulator performance in obstructive sleep apnoea (OSA) patients

ational Health and Medical Research Council0 个研究点目标入组 180 人开始时间: 2010年1月6日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•Aged 25-70 years
•At least 2 OSA symptoms (snoring, choking arousals or witnessed apneas, excessive daytime sleepiness)
•Full Diagnostic polysomnogram showing an apnea/hypopnea index >15 events/hr, central apnea index <5/hr
•untreated for OSA
•Live in Adelaide (not country patients)
•Full private standard driving license, drive at least 2 hours per week and have been driving in Australia for at least 2 years.

•History of significant head injury
•History of alcohol or drug abuse
•History of central nervous system disease (e.g. past history of stroke)
•Current use of medication which may affect driving (e.g. sedating antihistamines and opiates, regular use of hypnotics and other sedating psychotropic or anticonvulsant medication)
•Sleep disorders such as narcolepsy, periodic limb movement disorder, restless legs syndrome, insomnia
•Significant medical co-morbidities likely to affect sleep (e.g. severe chronic obstructive pulmonary disease (COPD) with forced expiratory volume in the first second (FEV1) <50%, significant cardiac failure (New York Heart Association [NYHA] 3 or 4), major depression).
•Professional drivers
•Night shiftworkers

发起方

ational Health and Medical Research Council