Intravenous Iron May Increase Depression Among Hemodialysis Patients

Completed

• Conditions: Hemodialysis Complication; Iron Deficiency Anemia; Depression

• Registration Number: NCT03157050
• Lead Sponsor: Benha University

Brief Summary

the aim of this study is to assess whether increased ferritin after intravenous iron therapy will lead to increased prevalence of major depression among treated patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-01-14
• Status Verified: 2017-05
• Primary Completion: 2017-05-15
• Study Completion: 2017-05-16
• Study First Submitted: 2017-05-16
• Study First Submitted QC: 2017-05-16
• Last Update Submitted: 2017-05-16
• Study First Posted: 2017-05-17
• Last Update Posted: 2017-05-17

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 112

Inclusion Criteria

1. age was above 19 years,
2. patient on maintenance hemodialysis,
3. patient had iron deficiency anemia (ferritin > 100 ng/ml)

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Exclusion Criteria

1. patient has history of depression or already using antidepressant medication,
2. Lack of ferritin level increase ≥ 50% from baseline level before IV iron administration,
3. patient already on oral or intravenous iron supplement

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in patient health questionnaire-9 score	on day 0 of start of intravenous iron and 1 week after completion of intravenous iron	change in patient health questionnaire-9 score before and after intravenous iron therapy