Trial on the efficacy of metformin in the treatment of Non-alcoholic steatohepatitis
Not Applicable
Recruiting
- Conditions
- on - alcoholic steatohepatitis (NASH)
- Registration Number
- SLCTR/2007/002
- Lead Sponsor
- Faculty of Medicine, University of Kelaniya,
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 170
Inclusion Criteria
* Patients with clinical, biochemical, radiological and histological evidence of NASH * No history of other possible aetiological factors for steatohepatitis such as significant alcohol consumption, medications
Exclusion Criteria
* Patients with diabetes mellitus * Patients with significantly elevated levels of total cholesterol and triglycerides requiring lipid lowering treatment * Patients with severe obesity * Patients with history of significant alcohol ingestion. *patients with history of taking medications known to cause NASH. * Patients with any other liver diseases * Patients with contraindications for metformin * Pregnant females * All patients with contraindications for liver biopsy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method End of treatment with metformin or placebo for 6 months [at 6 months]<br>
- Secondary Outcome Measures
Name Time Method one [None]<br>