effect of antilipidemic drug Simvastatin with commercially available bone graft in regeneration of bone loss in chronic periodontal disease
Phase 2
Completed
- Conditions
- Health Condition 1: null- Systemically healthy patients with Chronic periodontitis with grade 2 furcation involvements
- Registration Number
- CTRI/2018/03/012740
- Lead Sponsor
- Darshanaa Arunachalam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 15
Inclusion Criteria
1. Presence of isolated grade II furcation defect
2. No recent history of antibiotic and periodontal therapy
Exclusion Criteria
1. Systemic illness
2. Allergic to SMV
3. Systemic statin therapy
4. Pregnant lactating woman
5. Tobacco users
6. Immunocompromised patients
Alcoholism
Unacceptable oral hygiene
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical- horizontal probing depth, vertical probing depth, vertical clinical attachment loss <br/ ><br>Radiographic- vertical defect depth in IOPA, horizontal defect depth in CBCT, vertical defect depth in CBCT, volume of the defect in CBCTTimepoint: 0, 3, 6 months
- Secondary Outcome Measures
Name Time Method full mouth mean plaque index, full mouth mean bleeding index, full mouth mean probing depth, full mouth mean clinical attachment loss, intervention tooth mean plaque index, intervention tooth mean bleeding index, intervention tooth mean probing depth, intervention tooth mean clinical attachment lossTimepoint: 0, 3, 6 months