Comparison of markers of Oxidative stress, Myocardial structure and function, Inflammation and Vascular structure and function between Incident hemodialysis and peritoneal Dialysis patients (COMIVID) an Observational Study

Not Applicable

Recruiting

• Conditions: End Stage Kidney Disease; Renal and Urogenital - Kidney disease

• Registration Number: ACTRN12609000049279
• Lead Sponsor: Baxter Healthcare

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-01-21
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

Age >18 yrs and < 85 years
End stage kidney disease eGFR< 30 ml/min/1.73m2

Exclusion Criteria

failure to gain informed consent
intolerance of glyceryl trinitrate

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Inflammatory measure pentraxin-3 (blood analysis)[Baseline and 6 and 12 months after starting peritoneal or hemodialysis]

Secondary Outcome Measures

Name	Time	Method
oxidative stress F2 Isoprostanes (blood measure)[Baseline and 6 and 12 months after starting hemodialysis or peritoneal dialysis];Blood oxidative stress[Baseline and 6 and 12 months after starting dialysis];Pulsewave analysis (Augmentation Index)[Baseline and at 6 and 12 months after starting dialysis];Pulsewave velocity[Baseline and at 6 and 12 months after starting dialysis]