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Correlation of blood oxidative stress markers and Melasma

Not Applicable
Conditions
Health Condition 1: L811- Chloasma
Registration Number
CTRI/2023/07/055286
Lead Sponsor
FATHER MULLER RESEARCH CENTRE
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Patients of age 18years and above.

2.Patients of all gender.

3.Patients diagnosed with melasma clinically with MASI score indicating severity.

Exclusion Criteria

1.Patients who are pregnant, active smokers, on hormonal therapy, consumption of antioxidant supplements.

2.Patients with vitiligo, psoriasis, facial melanosis excluding melasma, other causes of skin pigmentation like acanthosis nigricans, sun tan, hair dye etc

3.Patients with endocrine and chronic systemic diseases like diabetes mellitus, heart failure, systemic lupus, etc.

4.Patients on drugs affecting antioxidant levels like hydroxychloroquine,immunosuppresive drugs

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Plasma glutathione, Total anti oxidant capacity and malondialdehyde of patients with MelasmaTimepoint: 0weeks or at presentation
Secondary Outcome Measures
NameTimeMethod
ILTimepoint: NI
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