EBUS-guided TBNA for Molecular Diagnostic of Mediastinal Lymph Nodes (LN)

• Conditions: Non Small Cell Lung Cancer
• Interventions: Procedure: EBUS_TBNA

• Registration Number: NCT00982605
• Lead Sponsor: Heidelberg University

Brief Summary

The purpose of this study is to perform molecular diagnostic in mediastinal lymph nodes of non-small cell lung cancer patients sampled by endobronchial ultrasound guided finde needle aspiration (EBUS-TBNA).

Detailed Description

NSCLC is a common cancer. Accurate and early staging has a significant impact on outcome. EBUS-TBNA of involved mediastinal lymph nodes is critical. Molecular markers could improve mediastinal staging.

Study Timeline

• Study First Submitted: 2009-09-22
• Study First Submitted QC: 2009-09-22
• Study First Posted: 2009-09-23
• Status Verified: 2009-10
• Study Start: 2009-10
• Last Update Submitted: 2009-10-05
• Last Update Posted: 2009-10-06
• Primary Completion: 2010-10
• Study Completion: 2011-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Age ≥ 18 years
• Samples are collected before surgery or before any therapy
• ECOG 0 or 1
• Clinical stage I-II, T1-2, N0-1, M0)
• Surgically respectable
• Patient with enlarged med. lymphnodes (control group)

Exclusion Criteria

• Previous RT/CHT
• Previous or current cancer of other entity

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
non small cell lung cancer	EBUS_TBNA	cancer patients

Trial Locations

Locations (1)

Thoraxklinik Heidelberg, Dept. of Pneumology and Respiratory Critical care; 🇩🇪 Heidelberg, Germany