The Efficacy of Regeneration Oil and Almond Oil on Split-Thickness Skin Graft Donor Sites: A Single-Blinded Randomized Controlled Trial

Not Applicable

• Conditions: Reepithilialized (healed) split-thickness skin graft donor sites; Z94.5; Skin transplant status

• Registration Number: DRKS00030072
• Lead Sponsor: Medizinische Universität Graz

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2016-06-25
• Study Start: 2022-08-25
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Patients with split-thickness skin graft (donor site thigh)

Exclusion Criteria

- Allergy or known allergic reaction to any of the oils used in the study
- Heart disease with a negative impact on skin blood flow
- Active tumor diseases
- congenital and acquired diseases of the immune system
- Anemia (hemoglobin <10g/dl or hematocrit <35%)
- Autoimmune diseases
- Acute/chronic kidney failure with serum creatinine values ??above 176 mmol/l or kidney disease requiring dialysis
- Liver cirrhosis, active liver infection/inflammation (hepatitis)
- Alcohol or drug addiction
- Severely underweight and cachectic patients (Body Mass Index <16)
- Thyroid dysfunction affecting the basal metabolic rate
- Diabetes mellitus
- Pregnancy, lactation
- Rejection of the study, lack of willingness to cooperate

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
- scar quality (Patient and Observer Scar Assessment Scale) after 1, 3, 6 months.<br>- itching (ITCH Man Scale) after 1, 3, 6 months

Secondary Outcome Measures

Name	Time	Method
scar discoloration (colorimetry) after 1, 3, 6 months