A double-blind randomised controlled trial of a natural oil-based emulsion containing allantoin versus aqueous cream for managing radiation-induced skin reactions in patients with cancer

Phase 3

Recruiting

• Conditions: Radiation-induced skin reactions in patients with cancer; Cancer - Any cancer; Skin - Dermatological conditions

• Registration Number: ACTRN12612000568819
• Lead Sponsor: Raymond Chan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2012-05-28
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 172

Inclusion Criteria

Participants in this study will all be patients receiving radical radiotherapy for lung cancer, breast cancer and head and neck cancer at the Royal Brisbane and Women’s Hospital . A sample of consecutive eligible and consented patients will be recruited into the study.
1. Age >18 years
2. Patients who have a definitive diagnosis of breast cancer, lung cancer or head and neck cancer
3. Patients who are receiving radiotherapy (>50 Gy) either as primary treatment or postoperative treatment to their chest, breast or head and neck.

Exclusion Criteria

1. Patients who are unable to consent
2. Patients with pre-existing skin rash, ulceration or open wound in the treatment area
3. Patients with known allergic and other systemic skin diseases even not directly affecting irradiated fields.
4. Patients with any known allergic reactions towards any ingredient of either the Moogoo Udder Cream (Registered Trademark) or the aqueous cream and failed the patch test.

Study & Design

• Study Type: Interventional
• Study Design: Not specified