A combined effect of low-frequency repetitive transcranial magnetic stimulation (rTMS) and cathodal transcranial direct current stimulation (tDCS) over non-lesional primary motor cortex on upper limb motor recovery in subacute stroke

Phase 2

Completed

• Conditions: 1. patients with subacute stroke diagnosed with incomplete hemiparesis, confirmed by CT(Computed tomography)/MRI(Magnetic resonance imaging); stroke

• Registration Number: TCTR20191027002
• Lead Sponsor: Faculty of Medicine, Chiang Mai University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2015-07-09
• Study Start: 2019-10-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

(1) Thai nationality
(2) age above 20, and not exceed 80
(3) Have been diagnosed with stroke within 3 months
(4) Can follow orders in 2 consecutive steps

Exclusion Criteria

(1) A recurrent stroke
(2) Other non-cerebrovascular disease; such as, brain tumors, brain injury
(3) Unstable medical conditions; such as, uncontrolled arrhythmia, acute coronary syndrome, congestive heart failure, end stage renal disease, pneumonia, urinary tract infection
(4) Use a Neurostimulator; such as, Vagal nerve stimulator, deep brain stimulator
(5) Use a pacemaker
(6) Metal inside the skull or in the ear
(7) History of epilepsy
(8) Have a seizure within 1 year
(9) History of substance abuse
(10) Pregnant
(11) Has been stimulated with rTMS or tDCS before.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Medical Research Council scale of upper extremity (MRC-UE) score,Medical Research Council scale of lower extremity (MRC-LE) score,Brunnstrom stage of arm (BS-ARM) score,Brunnstrom stage of hand (BS-HAND) score,Fugl-Meyer upper extremity motor score (FMA-UE) prior the intervention, immediately after intervention and 1 week after intervention ratio scale,Fugl-Meyer upper extremity motor score (FMA-UE) score,Wolf motor function test - Functional ability (WMFT- FAS) prior the intervention, immediately after intervention and 1 week after intervention ratio scale,Wolf motor function test - Performance time (WMFT-TIME) prior the intervention, immediately after intervention and 1 week after intervention ratio scale

Secondary Outcome Measures

Name	Time	Method
/A N/A N/A