A clinical trial to study the effects of adding the novel treatment rTMS (application of magnetic fields to brain) for people suffering from obsessive-compulsive disorder who have not improved adequately with standard treatment with medicines.
Phase 3
Completed
- Conditions
- Health Condition 1: null- Obsessive-compulsive disorderHealth Condition 2: F42- Obsessive-compulsive disorder
- Registration Number
- CTRI/2012/09/003031
- Lead Sponsor
- ational Institute of Mental Health and Neuro Sciences NIMHANS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1.Age- >= 18yrs
2.Diagnosed OCD since at least one year â?? (confirmed with MINI)
3.Partial (25-35% reduction in YBOCS score) or no response ( <25% reduction in YBOCS score) after adequate trial to one or more SSRI trial
4.Has current residual symptoms (YBOCS â?? >=16 / CGI-I - >= 4)
5.No medication/treatment change since 6 weeks
Exclusion Criteria
1.Contraindications for TMS
i)Metal implants
ii)Pacemaker
iii)Primary seizure disorder
2.Comorbid psychotic, bipolar disorder
3.Comorbid severe depression (HAM-D >= 28)
4.Comorbid active substance use disorder (apart from nicotine use disorder)
5.Medication change (for OCD) within past 6 weeks
6.Undergoing concomitant behavioural therapy
7.Unstable medical conditions, pregnancy, or breastfeeding
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method