The clinical effect of length of pre-transfusion storage of blood

Completed

• Conditions: Anaemia; Haematological Disorders; Other anaemias

• Registration Number: ISRCTN06273643
• Lead Sponsor: Record provided by the NHS Trusts Clinical Trials Register - Department of Health (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2003-09-12
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

1. Patients 18 and over with a haematological disorder requiring regular red cell transfusion (eg myelodysplastic syndrome, aplastic anaemia, etc)
2. Able to give informed consent
3. Serum creatinine <200 umol/l within past 2 months

Exclusion Criteria

Not provided at time of registration

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
48-hour post transfusion haemoglobin (Hb) increment.

Secondary Outcome Measures

Name	Time	Method
1. Changes in red cell 2,3-DPG concentration and Hb-oxygen affinity (P50)<br>2. Subsequent changes in Hb at 14 days and before next transfusion<br>3. Changes in patients' quality of life (QOL) as measured by SF-36 health survey and a visual analogue scale