Distal-Radial Approach using transdermal NitroGlycerin patch

Not Applicable

• Conditions: Angina pectoris; D000787

• Registration Number: JPRN-jRCTs051210128
• Lead Sponsor: Murai Kota

Brief Summary

The results of this study suggest that pretreatment with a nitroglycerin patch improves DRA puncture success rates and reduces the number of punctures for successful DRA. This may be due to the dilatation of the distal radial artery diameter.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-12-01
• Study Completion: 2023-03-31
• Results First Posted: 2023-09-15
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

1. Patients aged 20 to 85 years at the time of consent
2. Patients with angina pectoris
3. Patients scheduled for coronary angipography (CAG) using the distal radial artery approach
4. Hospitalized the day before CAG
5. Patients scheduled for CAG using a Glidesheath Slender with an internal diameter of 5 French size.
6. Patients with written consent from the patient

Exclusion Criteria

1. Patients taking or applying nitric acid, nitrate ester, calcium channel blockers, and nicorandil.
2. Patients who are scheduled for provocation study of vasospastic angina.
3. Patients with previous catheterization or treatment from the ipsilateral distal radial artery.
4. Patients with unstable angina or acute coronary syndrome.
5. Patients with hypersensitivity to nitric acid and nitrite ester drugs.
6. Patients with hypotension at the time of obtaining consent (systolic blood pressure less than 90 mmHg).
7. Patients with severe anemia (hemoglobin less than 9.0g/dL) at the time of obtaining consent.
8. Patients with glaucoma, cerebral hemorrhage or head injury within 1 month.
9. Pregnant women, lactating women.
10. Patients taking phosphodiesterase 5 inhibiter or guanylate cyclase stimulator.
11. Patients who have already participated in other clinical trials or plan to participate in other clinical trials during this study.
12. Patients who have been judged inappropriate for participation in the study by the investigator or sub-investigator for any other reason.

Study & Design

• Study Type: Interventional
• Study Design: Not specified