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临床试验/NCT03910855
NCT03910855已完成不适用

Investigating the Impact of Mindfulness on Psychological Well-being of Stroke Survivors and Their Caregivers: A Randomized Controlled Trial.

Singapore General Hospital2 个研究点 分布在 1 个国家目标入组 63 人开始时间: 2018年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
63
试验地点
2
主要终点
Cohen Perceived Stress Scale, PSS

研究概览

简要总结

This study will employ a randomized control design. Stroke survivors and family caregivers will be recruited for the study, and randomized either to receive mindfulness-based intervention or health education. Both programs consist of 4 2-hour sessions. Participants of the mindfulness-based intervention (MBI) will be taught and guided in practice of psychosocial interventions that are focused on (1) stress management and coping skills, (2), body awareness and movement, (3) feelings of empathy and compassion and (4) motivation for rehabilitation. Participants of the health education program (HEP) will learn and discuss topics related to self-care and post-stroke management. Measures will be administered prior to and on completion of the intervention, and at 3-month follow-up. They will be used to assess symptoms associated with depression, anxiety, stress, perceived quality of life and participant characteristics such as personality variables.

详细描述

Stroke prevalence is 3-4% among Singaporeans above the age of 50, and will rise with our aging population. Stroke survivors face many concerns, including physical, psychological, cognitive and psychosocial consequences of stroke, as well as impaired functioning and quality of life. They often rely on their family for physical, cognitive and emotional support in order to perform daily functional activities. Dependence on family members has been shown to affect the physical, mental and emotional well-being of caregivers of stroke survivors. Research indicates that the long-term demands of caring for a stroke survivor puts a strain on caregivers who may not be able to provide the appropriate amount of care required to manage the needs of stroke survivors over time.

Mindfulness-based interventions (MBIs) are increasingly being offered as psychotherapeutic interventions for individuals who suffer from medical conditions such as stroke, and for their long-term family caregivers. Several review studies have shown that MBIs, specifically for long-term conditions, enhanced the ability to cope with physical difficulties, improved mental and emotional well-being as well as overall quality of life, promoting better health outcomes. A systematic review investigating the use of MBIs with stroke survivors found that psychological, physiological and psychosocial outcomes were improved, such as anxiety, depression, mental fatigue and overall quality of life (Lawrence et al., 2013).

However, there are limited data for stroke survivors and their caregivers especially among Asians. Furthermore, there is little attention to study the interaction between participants characteristics and MBIs to determine whether there are any specific moderators that help to maximize the therapeutic outcomes of MBIs (Shaprio et al., 2011). Although there are growing number of studies correlating personality traits and dispositional mindfulness (Hanley, 2016; Giluk, 2009), little research has been done to examine personality traits as moderators to treatment outcome. Research focusing the the five-factor model of personality has demonstrated that the five personality traits have different strengths of correlation with the dispositional mindfulness. Among the traits, neuroticism displayed the strongest negative correlation with depositional mindfulness while conscientiousness displayed the strongest positive correlation with depositional mindfulness.

This study will be the first to examine the moderating effects of personality traits on the impact of mindfulness-based intervention in terms of depression, anxiety, stress and perceived quality of life of stroke survivors and their family caregivers. Furthermore, this study will evaluate and compare the impacts of mindfulness-based intervention and health education on the psychological well-being of both the participants. Findings will encourage the development of future strategies to understand the variability in treatment response and prognosis as well as to address individual differences with relevant psychotherapy skills.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
21 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Stroke survivors and/ or their
  • Family Caregivers
  • Comprehends and provides consent independently

排除标准

  • Cognitively impaired individuals with a MMSE score of less than 20, and a MoCA score of less than 23.

结局指标

主要结局

Cohen Perceived Stress Scale, PSS

时间窗: An average of 1 Month

A 10-item measure evaluating the perception of stress.

Centre for Epidemiologic Studies Depression Scale (CES-D)

时间窗: An average of 1 Week

A 20-item measure for epidemiological research on depression.

Stroke Specific Quality of Life Scale (SS-QOL)

时间窗: An average of 1 month

A 49-item self-report questionnaire designed to measure the heath related quality of life specific to stroke survivors across 12 domains.

Stroke Impact Scale (SIS)

时间窗: An average of 1 week

A 64-item questionnaire that assesses across 8 domains

Short-Form-36 (SF-36)

时间窗: A range from 4 to 52 weeks

A 36-item self-report survey of health, including physical and mental health. Higher scaled scores reflect better quality of health.

The State-Trait Anxiety Inventory, STAI

时间窗: State: Current state, Trait: An average of 1 month

The STAI is a commonly used measure of trait and state anxiety.

次要结局

  • The Big Five Personality Inventory, BFI(An average of 1 month)
  • Five Facet Mindfulness Questionnaire, FFMQ(An average of 1 month)
  • Zarit Burden Inventory (ZBI)(An average of 1 month)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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