Childhood Body Composition and Brain Structure and Function
Completed
- Conditions
- Healthy
- Registration Number
- NCT01822054
- Lead Sponsor
- Arkansas Children's Hospital Research Institute
- Brief Summary
The specific aim of this research project is to use MRI methods to evaluate and compare brain structure and function in normal weight and obese children age 8-10 years.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 27
Inclusion Criteria
- Healthy normal weight or obese children
- Parental report of full-term gestation
- Parental report of birth weight between 5th-95th percentiles
- Parental report of breastfeeding or cow's milk formula fed during infancy
- Right hand dominance
Exclusion Criteria
- Maternal diabetes
- Maternal alcohol, tobacco or drug use during pregnancy
- Chronic sleep disorder
- History of psychological or psychiatric diagnosis
- History of neurological impairment or injury
- Surgical implant or other foreign object in the body which may be a MRI safety concern
- Dental work which may cause artifacts in MRI
- Claustrophobia
- High likelihood of inability to tolerate loud noise from the MRI scanner
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Brain structure 8 - 10 years of age We will use high resolution volumetric MRI and DTIto measure the brain structure of these children
- Secondary Outcome Measures
Name Time Method Brain Function 8-10 years of age We will use high resolution fMRI to measure the brain function under different cognitive paradigms
Trial Locations
- Locations (1)
Arkansas Children's Nutrition Center
🇺🇸Little Rock, Arkansas, United States