Effects of Maternal Body Composition on Offspring Brain Structure and Function

Active, not recruiting

• Conditions: Brain Function

• Registration Number: NCT01822067
• Lead Sponsor: Arkansas Children's Hospital Research Institute

Brief Summary

The specific aim of this study is to use MRI methods to evaluate and compare brain structure and function in two groups of full-term neonates at two-weeks of age: those born of obese mothers and those born to normal weight mothers.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-08
• Study First Submitted: 2013-02-26
• Study First Submitted QC: 2013-04-01
• Study First Posted: 2013-04-02
• Status Verified: 2023-12
• Last Update Submitted: 2025-01-28
• Last Update Posted: 2025-01-30
• Primary Completion: 2025-06
• Study Completion: 2025-12

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• the participant must be enrolled in the Arkansas Children's Nutrition Center (ACNC) Glowing study and be about 2 weeks of age +/- 3days

Exclusion Criteria

• none specified

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Brain Structure	Age 2 weeks	We will use high resolution volumetric magnetic resonance imaging (MRI) and Diffusion tensor imaging (DTI) to measure the brain structure of 2 week old infants

Secondary Outcome Measures

Name	Time	Method
Brain Function	Age 2 weeks	We will use high resolution Resting state functional magnetic resonance imaging (rsfMRI) to measure the brain function of 2 week old infants

Trial Locations

Locations (1)

Arkansas Children's Nutrition Center; 🇺🇸 Little Rock, Arkansas, United States