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Clinical Trials/NCT05048264
NCT05048264
Terminated
Not Applicable

Corticosteroid Injections Administered Under Ultrasound Guidance to Diabetic Patients and the Effect on Blood Glucose

Duke University1 site in 1 country38 target enrollmentMay 4, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Diabetes Mellitus
Sponsor
Duke University
Enrollment
38
Locations
1
Primary Endpoint
Change in blood glucose measures
Status
Terminated
Last Updated
last year

Overview

Brief Summary

The purpose of this study is to measure the effect of various corticosteroids administered to the shoulder, knee and hip joints in diabetic patients on resultant blood glucose readings.

Detailed Description

The purpose of this study is to measure the effect of various corticosteroids administered to the shoulder, knee, and hip joints in diabetic patients on resultant blood glucose readings. Corticosteroid injections (CSI) are frequently used in orthopedic settings in order to treat a wide array of orthopedic issues, including osteoarthritis, bursitis, tendinitis, and many others. The effect of diabetes on the musculoskeletal system and its role in orthopedic disease has been well-documented. Current evidence demonstrates that corticosteroids, even when administered through a local musculoskeletal injection, can lead to temporary increases in blood glucose. Ultrasound guidance was not explicitly used in any of the studies examining the impact of steroids on blood glucose. The utilization of ultrasound guidance has been shown to increase accuracy when performing injections into the subacromial space as well as the glenohumeral joint when compared to palpation/landmark-guided injections.

Registry
clinicaltrials.gov
Start Date
May 4, 2023
End Date
September 16, 2024
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Known diabetic patients ages 40-75 undergoing clinically indicated standard of care corticosteroid shoulder, knee and hip joint injection
  • Ability to perform daily blood glucose testing
  • Can receive and send text messages

Exclusion Criteria

  • Previous joint arthroplasty
  • Corticosteroid injection at other sites in the body within the past month
  • Systemic corticosteroid within the last month other than asthma inhaler
  • Anyone who are unable to read and/or understand English
  • Pregnant women (self-report)

Outcomes

Primary Outcomes

Change in blood glucose measures

Time Frame: Baseline & 2 weeks

Reported daily glucose measures from baseline to two week after injection

Study Sites (1)

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