Concurrent chemo-radiotherapy(CCRT) with concomitant boost radiotherapy(CBRT) in locally advanced head and neck cancers.
Phase 4
- Conditions
- Health Condition 1: C139- Malignant neoplasm of hypopharynx,unspecifiedHealth Condition 2: C109- Malignant neoplasm of oropharynx,unspecified
- Registration Number
- CTRI/2021/06/034087
- Lead Sponsor
- Indira Gandhi Medical College Shimla
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Histology â?? squamous cell carcinoma.17
• Stage III, IV A and IV B.
• Previously untreated patients.
• Hb > 10gm%.
• Pre-treated leucocyte count of > 4000/cu mm.
• Platelet count > 100,000/cu mm.
• Normal renal and liver function tests.
• Karnofsky performance status αα>= 70.
Exclusion Criteria
• Histology other than squamous cell carcinoma.
• Sites other than oropharynx, hypopharynx, and larynx.
• Age > 70yrs.
• Deranged RFT / LFT.
• Previous treatment with RT/ Chemotherapy.
• Any prior/ synchronous malignancy.
• Hypersensitivity to platinum agents.
• Lymph nodes extending behind the spinal cord.
• Karnofsky performance status < 70.
• Distant metastasis
Study & Design
- Study Type
- PMS
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method