Effect of Remote Ischemic Preconditioning on Cardiac Function After Cardiac Surgery

Patrick Meybohm2 sites in 1 countryFebruary 2009

ConditionsAtrial Fibrillation Ventricular Arrythmias Myocardial Injury Cardiac Function

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: Atrial Fibrillation
Sponsor: Patrick Meybohm
Locations: 2
Primary Endpoint: New onset of atrial fibrillation
Status: Withdrawn
Last Updated: 14 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to evaluate the effects of Remote Ischemic Preconditioning on cardiac function in patients undergoing cardiac surgery compared to control intervention.

Detailed Description

In detail, we will focus on new onset of atrial fibrillation, ventricular arrhythmias, myocardial injury, and cardiac function. Furthermore, we aim to investigate underlying pathways of RIPC in modifying the perioperative stress response.

Registry

clinicaltrials.gov

Start Date

February 2009

End Date

February 2009

Last Updated

14 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Patrick Meybohm

Responsible Party

Sponsor Investigator

Principal Investigator

Patrick Meybohm

PD Dr.

University Hospital Schleswig-Holstein

Eligibility Criteria

Inclusion Criteria

•Patient undergoing heart surgery on cardiopulmonary bypass

Exclusion Criteria

•Emergency cases
•Myocardial infarction up to 7 days prior to enrollment
•Ejection fraction less than 30%
•Inability to give informed consent

Outcomes

Primary Outcomes

New onset of atrial fibrillation

Time Frame: Within 30 days after surgery

Secondary Outcomes

Ventricular arrhythmias, myocardial injury, cardiac function. Underlying pathways of Remote Ischemic Preconditioning in modifying the perioperative stress response.(Within 24 hours after surgery)