Respiratory system evaluation in treatment of acute pulmonary exacerbation in children and adolescents with Cystic Fibrosis

Not Applicable

Recruiting

• Conditions: Cystic Fibrosis; C06.689.202

• Registration Number: RBR-489ww6
• Lead Sponsor: niversidade do Estado de Santa Catarina

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-03-04
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Children and adolescents with CF; from one month to 15 years of age; hospitalized to IVA for treatment of acute pulmonary exacerbation; oriented; collaborative, in the case of children older than five years; and without neurological deficit; without auditory deficit; without visual deficit; they may not be in invasive mechanical ventilation support.

Exclusion Criteria

Children / adolescents who are unable to perform or terminate spirometry; unable to perform or terminate IOS; unable to perform or terminate functional/exercise capacity tests; requiring surgical intervention; requiring ventilatory support.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcomes: pulse oscillometry parameters (IOS), presented in kilopascal-kPa and percentages of predicted. Will be performed at moments before, during and after admission to IVA.<br><br><br><br>;Spirometry parameters presented in liter (L), liter per second (L / s) and percentages of predicted. Will be performed at moments before, during and after admission to IVA.;Performance on functional / exercise capacity assessment tests (total number of repetitions in the sit and stand test, total time of the step test). Will be applied at the beginning and at the end of the hospital stay.

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes: score of clinical scores for acute pulmonary exacerbation (CFCS and CFFS) and anthropometric data (mass in kilograms-kg, height in meters-m and BMI in kg/m 2). They will be evaluated the moments before, during and after admission to IVA.