Pressure Support During Chest Wall Compression

Not Applicable

Completed

• Conditions: Respiration, Artificial; Critical Care
• Interventions: Device: Chest wall compression plus increase of 10 cmH2O in inspiratory pressure during Pressure Support Ventilation for ten minutes in chest.; Device: Chest wall compression for ten minutes in chest

• Registration Number: NCT01155648
• Lead Sponsor: Hospital de Clinicas de Porto Alegre

Brief Summary

The purpose of this study is to compare two physiotherapy techniques: chest wall compression versus chest wall compression plus increase of 10 cmH2O in inspiratory pressure.

Detailed Description

1. After being placed in the supine position in bed, with head angle elevation at 30°, patients were randomized to:group 1 (G1): chest wall compression for ten minutes in chest or group 2 (G2): chest wall compression plus increase of 10 cmH2O in IP in PSV for ten minutes in chest.

2. Clinical variables and APACHE II were registered.

3. Parameters analyzed at the beginning (1) and at the end (2) of the protocol were: variation of peak pressure (ΔPp=Pp2-Pp1),variation of tidal volume (ΔVT =VT2-VT1), variation of dynamic compliance (ΔCdyn= Cdyn2-Cdyn1).

4. The amount of variation of mucus secretion aspirated (ΔSa= Sa2-Sa1) at the end was also measured

Study Timeline

• Study Start: 2008-05
• Primary Completion: 2009-06
• Study Completion: 2010-05
• Status Verified: 2010-06
• Study First Submitted: 2010-06-23
• Study First Submitted QC: 2010-07-01
• Last Update Submitted: 2010-07-01
• Study First Posted: 2010-07-02
• Last Update Posted: 2010-07-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

• Patients on mechanical ventilation over 48 hours
• With ventilatory drive
• Hemodynamically stable MAP> 60 mmHg
• With treatment of respiratory therapy

Exclusion Criteria

• Contra indication of increased positive inspiratory pressure
• Peak pressure in the upper airway > 40 cmH2O
• Osteoporosis diagnosis
• Deny to participate in the study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
PSV group.	Chest wall compression plus increase of 10 cmH2O in inspiratory pressure during Pressure Support Ventilation for ten minutes in chest.	Chest wall compression plus increase of 10 cmH2O of PSV.
chest wall compression group	Chest wall compression for ten minutes in chest	Chest wall compression

Primary Outcome Measures

Name	Time	Method
Variation of mucus secretion aspirated.	Two years

Secondary Outcome Measures

Name	Time	Method
Hemodynamic and pulmonary parameters.	Two years	The hemodynamic and pulmonary parameters were collected: Hart rate (HH), respiratory rate (f), mean arterial pressure (MAP) and peripheral arterial saturation of oxygen (SpO2); peak inspiratory pressure (Ppeak),and Tidal volume (VT) measured in the ventilator, dynamic compliance (Cdyn calculated through the formula VT/ Ppeak - PEEP)

Trial Locations

Locations (1)

Federal University of Rio Grande do Sul, Hospital de Clínicas de Porto Alegre; 🇧🇷 Porto Alegre, Rio Grande do Sul, Brazil