Spinal cord stimulation for the treatment of central pain in Multiple Sclerosis

Not Applicable

Completed

• Conditions: Topic: Neurological; Subtopic: Neurological (all Subtopics); Disease: Nervous system disorders; Nervous System Diseases; Multiple sclerosis

• Registration Number: ISRCTN36818685
• Lead Sponsor: Walton Centre for Neurology and Neurosurgery (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-04-23
• Study Completion: 2010-06-30
• Last Update Posted: 19 February 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

1. Group 1: Confirmed MS with central pain
2. Group 2: Peripheral nerve injury pain
3. Both groups eligible for spinal cord stimulation
4. Group 3: Age- and gender-matched healthy controls
5. Male and female, aged 18 years or older

Exclusion Criteria

1. Unsuitable for spinal cord stimulation
2. High intake of opiates
3. High levels of psychological distress

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in pain scores measured by daily pain diaries, measured on day 7 of the trial

Secondary Outcome Measures

Name	Time	Method
Comparison of QST measurements in MS patients with and without stimulation, measured on day 5 of the trial, when the second sensory testing is complete