Effect of a multimodal physiotherapy intervention to target balance capacity in Huntington s disease a double blind randomized clinical trial

Not Applicable

• Conditions: Huntington's disease; C10.228.140

• Registration Number: RBR-463yhb3
• Lead Sponsor: niversidade de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-08-01
• Study Completion: 2022-12-20
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Diagnosis of Huntington's Disease and confirmed by genetic test showing trinucleotide repeat number above 39; History of balance and gait impairments; and able to walk 10 minutes continuously and independently or with supervision indoors without walking aid

Exclusion Criteria

Mini-Mental Status Examination MMSE below 15 points; unstable medication over the past 3 months; and hearing or visual problems interfering with the tests or training

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assess balance as a primary outcome using the Mini-BESTest (Mini Balance Evaluation Systems Test) to analyze balance as a primary outcome. The Mini-BESTest is a 14-item balance test (total sum of 28 points), scored from 0 to 2 (higher score, better balance). We expect an improvement on balance in the post-intervention period. We will observe whether this improvement will be maintained after 6 months of follow-up by Mini-BESTest