The Effect of remifentanil on Mini-mental status examination after electroconvulsive therapy in major depressive patients.
Phase 2
- Conditions
- The Patients With Major Depressive Disease.Severe depressive episode with psychotic symptoms
- Registration Number
- IRCT201608086280N10
- Lead Sponsor
- Vice chancellor for research, Guilan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Inclusion Criteria: 60 patients between 18-60y; major depression; meet the DSM-TR IV ;. elective electroconvulsive therapy will performed only in 1th.
The exclusion criteria : the patients with ASA class IV ; mild to moderate cognitive disorder; emergency condition; history of cardiovascular disease; mental retardation ; uncontrolled hypertension.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cognitive Disorder after ECT. Timepoint: Before the ElectroConvulsive Therapy and 5 and 24 hours after ECT procedure. Method of measurement: MMSE Questionnaire 24-30, no cognitive problem 23-18mild cognitive problem 0-17,sever cognitive problem.
- Secondary Outcome Measures
Name Time Method Heart Rate. Timepoint: before electro convulsive therapy /5 and 24 hour after ECT. Method of measurement: ECG.;Blood Presssure. Timepoint: the time before electro convulsive therapy /5 and 24 hour after ECT. Method of measurement: NonInvasive Blood Pressure .;Seizure Duration . Timepoint: before electro convulsive therapy /5 and 24 hour after ECT. Method of measurement: By chronometer.