Communication in context in neurotypical and ASD populations

Recruiting

• Conditions: Autism; autism spectrum disorder; 10010118

• Registration Number: NL-OMON52774
• Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 156

Inclusion Criteria

- Between 18 and 40 years of age
- Normal or corrected-to-normal vision
- Normal uncorrected hearing
- Eligibility for MRI (i.e. no metals in or around the body, metal fragments,
pacemakers, claustrophobia)
- Body mass index between 18.5 and 30
- Willingness and ability to give written informed consent and willingness and
ability to understand the nature and content, to participate and to comply with
the study requirements.
- Education level MBO-4 or higher
- Capable to read and comprehend the Dutch language

ASD patients:
- Current ASD diagnosis

Exclusion Criteria

- Current alcohol or drug abuse
- Use of psychotropic medication or systemic glucocorticoids
- History of neurological disorders (e.g., traumatic brain injury, seizure
history)
- Any severe or chronic systemic disease
- Severe cognitive impairment or a history of organic mental disorder
- Use of recreational drugs over a period of 72 hours prior to MRI scanning,
and use of alcohol within the last 24 hours before MRI scanning
- History of neurological treatment or current neurological treatment
- History of head surgery
- Claustrophobia
- Epilepsy
- Pregnancy
- Dyslexia

All patients:
- Current psychotic, bipolar, substance-related, severe personality disorder,
or mental retardation
- Current severe depressive disorder
- Prominent current suicidal risk or homicidal ideation

ASD patients:
- Current SAD diagnosis

High-socially anxious (SA) individuals:
- Current ASD diagnosis

Neurotypical participants:
- (lifetime history of) ASD or SAD diagnosis
- Current DSM-5 axis 1 disorder

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified