Propofol and remifentanil requirements after acute ethanol intake in clinical settings
Completed
- Conditions
- Interaction of acute ethanol intravenous intake with propofol (general anesthetic) and remifentanil (opioid)SurgeryAnaesthesia
- Registration Number
- ISRCTN73421343
- Lead Sponsor
- Theagenio Anticancer Hospital of Thessaloniki (Greece)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
Female surgical patients on general anesthesia
Exclusion Criteria
Alcoholic patients, patients in abstinence
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction of propofol and remifentanil requirements
- Secondary Outcome Measures
Name Time Method Degree of reduction, side-effects
Related Research Topics
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How does acute ethanol intake modulate GABA and mu-opioid receptor pathways to alter propofol/remifentanil requirements in anesthesia?
What comparative effectiveness data exist for propofol/remifentanil vs. standard-of-care anesthetics in ethanol-intoxicated surgical patients?
Which biomarkers correlate with propofol and remifentanil dose adjustments after acute ethanol ingestion in surgical patients?
What adverse events occur when combining propofol, remifentanil, and acute ethanol in clinical anesthesia, and how are they managed?
Are there alternative anesthetic agents or combinations to propofol and remifentanil for patients with acute ethanol intoxication?