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Clinical Trials/NCT05157009
NCT05157009
Enrolling By Invitation
Not Applicable

Immediate Implants in Damaged Sockets With Simultaneous Bone Reconstruction vs. Immediate Implants in Intact Sockets and no Reconstruction

Verdugo, Fernando, DDS1 site in 1 country50 target enrollmentOctober 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Tooth Loss
Sponsor
Verdugo, Fernando, DDS
Enrollment
50
Locations
1
Primary Endpoint
Number of individuals with low pink esthetic outcomes as assessed by pink esthetic scores (PES)
Status
Enrolling By Invitation
Last Updated
3 years ago

Overview

Brief Summary

To evaluate immediate implant placement feasibility and esthetic outcomes in severely damaged sockets that received simultaneously bone reconstruction (cortical bone shield) and implant placement versus intact sockets that needed no reconstruction and had immediate implant placement.

Detailed Description

The present clinical trial aims at demonstrating facial bone regeneration on sites that presented large buccal bone dehiscences \& vertical bone loss and evaluate the feasibility of performing simultaneous bone augmentation and implant placement, comparing the outcomes with sites that had intact sockets that did not require reconstruction. A secondary objective was to evaluate pink esthetics and marginal bone levels at final follow-up.

Registry
clinicaltrials.gov
Start Date
October 1, 2021
End Date
December 31, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Verdugo, Fernando, DDS
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • individuals 20 Years and older
  • Patients requiring single implants to replace missing teeth to restore masticatory function and esthetics.
  • ASA1 or ASA2 (American Society of Anesthesiologists)
  • Healthy individuals with good oral hygiene and motivation
  • No systemic uncontrolled diseases
  • Not taking drugs known to modify bone metabolism

Exclusion Criteria

  • Individuals with untreated \& generalized severe periodontitis
  • Smokers (\>5 cigarettes/day)
  • Poor oral hygiene
  • Diabetes (HbA1C \>6.5% as cutoff value)
  • Uncontrolled cardiovascular disease
  • Poor overall health (ASA IV)

Outcomes

Primary Outcomes

Number of individuals with low pink esthetic outcomes as assessed by pink esthetic scores (PES)

Time Frame: 12 months

pink esthetics scores (PES) as proposed by Belser et al. Values 0-10 were 10 is the best esthetic outcome.

Evaluate implant placement feasibility & success rate at 12 months

Time Frame: 12 months

evaluate implant success following Karoussis et al. success criteria

Secondary Outcomes

  • Number of participants with >0.2mm of marginal bone levels(12 months)
  • Band of keratinized tissue: clinical presence or absence(12 months)
  • Implant transparency: clinical presence or absence(12 months)

Study Sites (1)

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