MRI Intervention_Evaluation and optimization of fluoroscopic MRT sequences for performing MR-assisted biopsy / microwave ablation / PTCD while avoiding ionizing radiatio

Not Applicable

Recruiting

• Conditions: C78.5; Secondary malignant neoplasm of large intestine and rectum; C78.7; K71.0; Secondary malignant neoplasm of liver and intrahepatic bile duct; Toxic liver disease with cholestasis

• Registration Number: DRKS00019208
• Lead Sponsor: Klinikum der Universität München, Campus Großhadern

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

Clinical indication for liver biopsy, local ablation therapy of liver tumors or drainage of the biliary tract.
The indication for intervention must be independent of the presented study.
- No contraindication to the MRI examination
- Platelets> 50,000 / mm3 (50 GPt / l)
- INR / PTT <1.5 times the upper normal value (patients taking anticoagulants can be included if no underlying blood coagulation abnormality has previously been determined)
- Signed informed of consent
- Age> 18 years

Exclusion Criteria

Lack of consent and / or inability to consent to the study
- Contraindications for an MRI examination, in particular implants, tattoos or piercings that are not suitable for MRI, limiting claustrophobia
- Contraindications for contrast media (only in the case of MR contrast media use):
o Known allergy to MR contrast media
o Severe renal insufficiency (GFR <30 ml / min)
- Contraindications to image-guided interstitial intervention
o Platelets <50,000 / mm3 (50 GPt / l)
INR / PTT> 1.5 times the upper norm value
Presence of a blood clotting abnormality

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Feasibility of MR interventions<br>Morbidity and mortality of MR interventions compared to CT intervention<br>Cost-effectiveness of the MR intervention compared to the CT intervention

Secondary Outcome Measures

Name	Time	Method
Visualization of the lesion with high sensitivity