Clinical Assessment of Injectable Flowable Composite With Giomer Based Technology Versus Smart Bioactive Restoration in Carious Class V Cavities (A Randomized Clinical Trial)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
- 试验地点
- 2
- 主要终点
- Assessment of Modified USPHS Criteria (Marginal discoloration) change over time
研究概览
简要总结
This study will compare between S-PRG-containing injectable flowable resin composite (Beautifil Flow Plus X) and smart bioactive flowable resin composite (Activa bioactive restorative) through evaluation of the modified USPHS clinical performance in patients with carious class V moderately deep cavities.
详细描述
Bioactive glass has an amorphous structure, whereas glass-ceramics are crystallized glasses and composites of a crystalline phase in a residual glassy phase. Bioactive glass consists solely of the elements found in the body material, mainly being silicon (Si), calcium (Ca), sodium (Na), phosphorous (P), and oxygen (O) . Among the diverse kinds of bioactive glass filler, surface pre- reacted glass ionomer (S-PRG) filler has already been used for a relatively long time in some specific commercial RBCs. Most studies investigating this material assortment have focused on ion-release degree and potentially associated antibacterial effects. The restoration's surface integrity may be a key factor determining the eventual clinical beneficial effect of the alleged antibacterial properties. The antibacterial efficacy of bioactive glass depends on the concentration of the ions released from the glass.
As inorganic bioactive fillers, S-PRGs have the additional ability to release ions. S-PRG filler is considered a multifunctional bioactive glass because it can release several types of ions including Al, B, F, Na, Si, and Sr. The released ions can exhibit a variety of bioactive behaviors, such as preventing fungal and bacterial adhesion, antibacterial activity, neutralizing acids, inhibiting demineralization, and enhancing remineralization.
The biological effects of S-PRG fillers have been studied for several types of oral pathogens. It was reported that the elute of the S-PRG filler has a protective effect against Streptococcus mutans. Moreover, the elute of S-PRG filler reduced the density and thickness of the formed biofilm.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
During treatment, the type of material will be concealed from the patient, and the patient will have no information which material will be used. The type of restoration will not mentioned in the patient's file. Instead, it will be replaced by a combination which the evaluators will be not familiar with. The operator will be blinded for the type of restoration during tooth preparation and was informed only at the time of restoration placement. The purpose of this discretion is to ensure double blinding both at the patient, as well as the evaluators level.
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ages 18 to 55 years.
- •Male or female patients.
- •Patients with no history of allergic reactions to methacrylate compounds and in good general health.
- •Patients with good general health.
- •Patients with good recall availability. Patients required Class V restoration
- •Vital teeth with normal appearance and morphology.
- •Absence of clinical symptoms of irreversible pulpitis, such as spontaneous pain or sensitivity to pressure.
- •Absence of clinical diagnosis of pulp exposure, fistula, swelling of periodontal tissues, and/or abnormal tooth mobility .
- •No defects and lesions for other operative intervention, occlusal and proximal contacts with adjacent teeth.
排除标准
- •Patients with history of any adverse reaction to clinical materials of the types to be used in the evaluation.
- •Pregnant and lactating females.
- •Any patients with medical and/or dental histories which could possibly complicate the provision of the proposed restoration and/or influence behavior and performance of the restorations in clinical service.
- •They are included in the evaluation of other restorative materials and systems involving the anterior and/or posterior teeth.
- •Patients who maintain an unacceptable standard of oral hygiene.
- •Teeth with noncarious cervical lesions.
- •Severe tooth sensitivity.
- •Non-vital or fracture or cracked teeth.
- •Tooth with defective restoration.
- •Teeth with advanced periodontal diseases.
- •There is evidence occlusal parafunctions and/or atypical tooth wear.
结局指标
主要结局
Assessment of Modified USPHS Criteria (Marginal discoloration) change over time
时间窗: Change between baseline,6 months and 12 months
Alfa: there is no visual evidence of marginal discoloration different from the color of the restorative material and from the color of the adjacent tooth structure. Bravo: there is visual evidence of marginal discoloration at the junction of the tooth structure and the restoration that has not penetrated along the restoration in a pulpal direction. Charlie: there is visual evidence of marginal discoloration at the junction of the tooth structure and the restoration, but the discoloration has penetrated along the restoration in a pulpal direction.
次要结局
- Assessment of Modified USPHS criteria. (Secondary caries) change over time(Change between baseline,6 months and 12 months)
研究者
Bassma Reda Abdelhafeez
Principle Investigator
Cairo University