ature and mechanism of cognitive deficits following chemotherapy: an (f)MRI study
- Conditions
- cognitive deficitsmemory and concentration problems10009841
- Registration Number
- NL-OMON31092
- Lead Sponsor
- Antoni van Leeuwenhoek Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
all groups:
-female
-sufficient proficiency in the Dutch language;cross-sectional part:
-participation in previous neuropsychological study
-having been treated with high-dose chemotherapy (CTC);prospective part, experimental group
-newly diagnosed breast cancer patients without distant metastases that will receive chemotherapy (ACdd + T);prospective part, control group
-newly diagnosed breast cancer patients without distant metastases that will not receive chemotherapy
Exclusion Criteria
-relapse and/or metastases
-excessive use of alcohol or drugs
-use of psychotropic medication
-neurologic or psychiatric disorders that may influence cognitive functioning
-conditions that preclude MRI examination
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method