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Clinical Trials/NL-OMON34510
NL-OMON34510
Completed
Not Applicable

ature and mechanisms of cognitive deficits following chemotherapy: an (f)MRI study - chemotherapy, cognition and (f)MRI

Antoni van Leeuwenhoek Ziekenhuis0 sites180 target enrollmentTBD
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Conditionscognitive deficitsmemory and concentration problems10009841

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
cognitive deficits
Sponsor
Antoni van Leeuwenhoek Ziekenhuis
Enrollment
180
Status
Completed
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
last year
Study Type
Observational invasive

Investigators

Sponsor
Antoni van Leeuwenhoek Ziekenhuis

Eligibility Criteria

Inclusion Criteria

  • •All groups:
  • •\-female, independent of menopausal status
  • •\-age under 70 years (to allow use of the same neuropsychological test battery)
  • •\-sufficient proficiency in the Dutch language;Experimental group:
  • •\-newly diagnosed breast cancer patients without distant metastases who will receive anthracycline\-based chemotherapy ;Breast cancer control group:
  • •\-newly diagnosed breast cancer patients without distant metastases who do not require chemotherapy;Healthy control group:
  • •\-healthy females, matched for age

Exclusion Criteria

  • •All groups:
  • •\-previous malignancies
  • •\-excessive use of alcohol or drugs
  • •\-use of psychotropic medication
  • •\-neurologic or psychiatric disorders that may influence cognitive functioning
  • •\-conditions that preclude MRI examination.;Experimental group and breast cancer control group:
  • •\-relapse and/or metastases
  • •\- treatment with trastuzumab (Herceptin)

Outcomes

Primary Outcomes

Not specified

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