Use of Morphine Gel Topically in Patients With Stage 2-3 Wounds

Phase 3

• Conditions: Wounds
• Interventions: Drug: morphine topical gel; Drug: placebo

• Registration Number: NCT00755989
• Lead Sponsor: Banner Health

Brief Summary

Morphine gel applied topically to wounds will reduce wound pain and decrease patients use of oral and intravenous pain medications, therefore reducing side effects.

Detailed Description

Patients will be randomized to receive either placebo (versa base gel) or morphine gel to wound. Patients receiving morphine gel will have a decrease in pain score and use less oral/intravenous pain medications.

Study Timeline

• Status Verified: 2008-09
• Study First Submitted: 2008-09-18
• Study First Submitted QC: 2008-09-18
• Last Update Submitted: 2008-09-18
• Study First Posted: 2008-09-19
• Last Update Posted: 2008-09-19
• Study Start: 2008-12
• Primary Completion: 2009-12
• Study Completion: 2009-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Signed and dated consent form & HIPAA
• > 18 yo
• Single stage 2-3 wound
• No allergy to morphine
• Alert and oriented (thinking ability clear and intact, physician approval)
• English language proficiency

Exclusion Criteria

• Allergy to morphine, codeine, or versa base, pts taking medications for acute condition, other than for the wound pain
• Patients with neuropathies
• Patients with respiratory conditions

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
2	morphine topical gel	Morphine gel
1	placebo	group to receive topical gel without morphine

Primary Outcome Measures

Name	Time	Method
Safety and efficacy with the use of morphine gel applied topically for pain control	1 year

Trial Locations

Locations (1)

Banner Good Samaritan Medical Center; 🇺🇸 Phoenix, Arizona, United States