Morphine Gel for Bedsores
- Conditions
- Decubitus Ulcer
- Registration Number
- NCT00007254
- Lead Sponsor
- University of Kansas
- Brief Summary
This study tests the effectiveness of a morphine-containing gel for reducing pain caused by pressure ulcers, also known as bedsores or pressure sores. We will apply the gel containing morphine, or the gel alone, directly onto painful pressure ulcers and compare the results.
- Detailed Description
In this study, we will apply a morphine-containing gel (or placebo) directly onto painful pressure ulcers. We will take participants off of any opioid-containing medications upon entry into the study. This allows us to measure any morphine that may enter into the bloodstream from the topically applied gel.
The purpose of this study is to examine the efficacy of the gel for pressure ulcer analgesia, as well as the systemic absorption of morphine from the topically applied gel. We will document the amount of pain medications taken by participants to determine whether the gel decreases the need for these drugs.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 75
- Presence of a Stage II pressure ulcer.
- Pressure ulcer must be painful.
- Primary Care physician must approve participation.
- Thinking ability must be clear and intact.
- Willing to change pain medication to oxycodone.
- Allergy to morphine, oxycodone or intrasite gel.
- Use of codeine- or morphine-containing medications.
- Use of pain medications for anything other than the pressure ulcer.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
The University of Kansas Medical Center
🇺🇸Kansas City, Kansas, United States
Kindred Hospital
🇺🇸Kansas City, Missouri, United States
The University of Kansas Medical Center🇺🇸Kansas City, Kansas, United States