A Multicenter, Randomized, Double-Blind, Crossover Study Comparing the Effect of MK0359 and Placebo in Adult Patients With Chronic Asthma

Merck Sharp & Dohme LLC0 sites56 target enrollmentStarted: September 2002Last updated: May 27, 2015

ConditionsAsthma

Overview

A study to test the effect of MK0359 in lessening the symptoms of asthma as compared to placebo.

•You are between the ages of 18 and 45
•You have had a history for at least a year of COPD symptoms
•Your current asthma treatment is limited to short-acting beta-agonists(such as albuterol)
•You have a history of smoking one pack of cigarettes per day for 7 years
•You will not be away from home for more than 5 days during the study

•You are unwilling to limit your alcohol use to less than 5 drinks per week
•You have been in a research study with an investigational drug or vaccine in the last 4 weeks
•You have donated blood in the last 4 weeks
•You have been hospitalized or had major surgery in the last 4 weeks
•You have been treated in the emergency room within the last 4 weeks or hospitalized within the last 3 months for your asthma
•You have a history of heart problems in the last 6 months
•You have a history of stomach problems
•You are unwilling to avoid grapefruit juice throughout the study

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