Whole-body Electromyostimulation Versus Conventional Low-volume Strength Training in Overweight Individuals

Not Applicable

• Conditions: Overweight and Obesity; Metabolic Syndrome
• Interventions: Other: Control; Other: Whole-Body Electromyostimulation (WB-EMS); Other: Standard Strength Training; Other: Low-volume Strength Training

• Registration Number: NCT03306056
• Lead Sponsor: University of Erlangen-Nürnberg Medical School

Brief Summary

The main purpose of this study is to compare the effects of whole-body electromyostimulation versus a conventional low-volume strength-training program, each combined with an individualized, weight-reducing diet, on the cardiometabolic risk profile, muscle strength, body composition, inflammatory markers and subjective health outcomes in overweight individuals at increased cardiometabolic risk.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-09-27
• Study First Submitted QC: 2017-10-09
• Study First Posted: 2017-10-10
• Study Start: 2017-11-01
• Status Verified: 2018-10
• Last Update Submitted: 2018-10-15
• Last Update Posted: 2018-10-17
• Primary Completion: 2020-09-30
• Study Completion: 2020-09-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Body Mass Index >25
• presence of at least 2 cardiometabolic risk factors

Exclusion Criteria

• Healthy persons or patients under age
• Overweight persons without any additional cardiometabolic risk factors
• Pregnancy, Lactation
• Psychological disorders, epilepsy, sever neurological disorders
• Participation in other exercise- or nutrition studies within the last 6 months
• acute cardiovascular disease
• malignant disease
• Rheuma
• Intake of anabolic drugs,
• Skin injuries in the area of electrode placements
• Electronic implants (defibrillator, pacemaker)
• Persons in mental hospitals by order of authorities or jurisdiction

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	Control	Nutritional therapy / no exercise
Whole-body Electromyostimulation	Whole-Body Electromyostimulation (WB-EMS)	Nutritional therapy combined with Whole-Body Electromyostimulation
Standard Strength Training	Standard Strength Training	Nutritional therapy combined with a Standard Strength Training program
Low-volume Strength Training	Low-volume Strength Training	Nutritional therapy combined with a low-volume Strength Training program

Primary Outcome Measures

Name	Time	Method
Metabolic Syndrome Z-Score (MetS-Z-Score)	12 weeks (baseline to 12 week follow-up assessment)	MetS-Z-Score will be calculated from each individual's measures of waist circumference, mean arterial blood pressure, triglycerides, and HDL-cholesterol, based on equations specific to sex.

Secondary Outcome Measures

Name	Time	Method
Muscle strength	12 weeks (baseline to 12 week follow-up assessment)	Muscle strength of the five major muscle groups (chest, upper back, lower back, abdominals, legs) will be assessed by using specific strength-training devices (Butterfly, Pull-down, Hyperextension, Abdominal Crunch, Leg-Press)
Body Composition	12 weeks (baseline to 12 week follow-up assessment)	Muscle mass, fat mass and body water will be measured by Bioelectrical Impedance Analysis (BIA)
Cardiorespiratory Fitness (CRF)	12 weeks (baseline to 12 week follow-up assessment)	CRF will be assessed by measuring Maximum Oxygen uptake (VO2max)
Inflammation status	12 weeks (baseline to 12 week follow-up assessment)	Inflammation will be assessed by measuring Levels of CRP and inflammatory cytokines and other inflammatory blood markers
Health-related quality of life	12 weeks (baseline to 12 week follow-up assessment)	Health-related quality of life will be assessed by using the standardized and validated EQ-5D-5L Questionnaire
Pain scores	12 weeks (baseline to 12 week follow-up assessment)	Pain scores will be assessed by using the standardized and validated Chronic Pain Grade Questionnaire (CPGQ)
Perceived stress	12 weeks (baseline to 12 week follow-up assessment)	Perceived stress will be assessed by using the standardized and validated Perceived Stress Questionnaire (PSQ)
Subjective work ability	12 weeks (baseline to 12 week follow-up assessment)	Subjective work ability will be assessed by using the standardized and validated Work Ability Index Questionnaire (WAI)

Trial Locations

Locations (1)

Department of Medicine 1, Hector Center for Nutrition, Exercise and Sports,; 🇩🇪 Erlangen, Germany