Insulin Resistance and Hypertensive Disorders in Pregnancy

Completed

• Conditions: Hypertension in Pregnancy; Diabetes Mellitus in Pregnancy

• Registration Number: NCT00412230
• Lead Sponsor: University of Messina

Brief Summary

The purpose of this study is to determine whether insulin resistance might affect the pathogenesis of hypertensive disorders in pregnancy since midtrimester. Furthermore, markers of vascular and placental injuries, of oxidative stress and inflammation will be evaluated.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-10
• Study First Submitted: 2006-12-15
• Study First Submitted QC: 2006-12-15
• Study First Posted: 2006-12-18
• Study Completion: 2008-06
• Status Verified: 2009-02
• Last Update Submitted: 2009-02-17
• Last Update Posted: 2009-02-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• PCOS, BMI>/=30
• previous pregnancy affected by hypertension or gestational diabetes
• thrombophilia
• Type I or II diabetes mellitus
• autoimmune diseases
• twin pregnancy
• renal diseases
• previous pre-eclampsia in relatives

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

University Hospital; 🇮🇹 Messina, Italy