EGAL: Environmental and Genetic Effects on Autism Longitudinal

Conditions: Autism
Autism Spectrum Disorder
10012562

Registration Number: NL-OMON51612

Lead Sponsor: Vrije Universiteit

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 1000

Inclusion Criteria

ASD diagnosis
>= 16 years old
Able to provide consent for themselves

To ensure most of the data can be used in our analyses, the following
additional inclusion criteria apply:
Consent to use four digits of postal code
European ethnicity

Exclusion Criteria

No ASD diagnosis
<16 years old
Non-European ancestry
No consent to use four digits of postal code
Not able to provide consent for themselves

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>-ASD case/control status<br /><br>-Autistic traits: Autistic traits are measured using validated questionnaires<br /><br>(e.g. Autism Quotient Short (AQ-short))<br /><br>-Self-reported comorbidities: Assessed comorbities include additional<br /><br>diagnoses, mood problems and insomnia. Comorbities are measured using validated<br /><br>questionnaires (e.g. Strengths and Difficulties Questionnaire (SDQ), Hospital<br /><br>Anxiety and Depression Rating Scale (HADS)) and self-report.<br /><br>-Self-reported quality of life. Quality of life is measured using the Cantril<br /><br>Self-Anchoring Scale: the Ladder and with validated, more in-depth quality of<br /><br>life questionnaires. In addition, quality of life is measured with questions on<br /><br>occupation history, and educational attainment.</p><br>

Secondary Outcome Measures