Function and Modulation of Fibulin-1 Assembly in Nucleus of Corneal Fibroblasts
- Conditions
- Function of Mitomycin C in Cornea
- Registration Number
- NCT01808495
- Lead Sponsor
- Far Eastern Memorial Hospital
- Brief Summary
The purpose of this study is to investigate the role of nuclear Fibulin-1 (FBLN1) in Human Corneal Fibroblasts under treatment of mitomycin C (MMC).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 5
Inclusion Criteria
- The frozen storage cells in liquid nitrogen were amplified from the residual corneal rim of the donors with more than 20 years old following penetrating keratoplasty.
Exclusion Criteria
- The donors were younger than 20 years old.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Modification of nuclear Fibulin-1 accumulation in suppressing gene expression 3 days post mitomycin C treatment
- Secondary Outcome Measures
Name Time Method