Estimation of Pulmonary Vascular Resistance by Contrast Echocardiography
Not Applicable
Completed
- Conditions
- Pulmonary Arterial Hypertension
- Interventions
- Procedure: 2D doppler echo with Definity solution
- Registration Number
- NCT02028299
- Lead Sponsor
- George Washington University
- Brief Summary
An echocardiogram using Definity contrast can provide the same information as the standard right heart catheterization.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 38
Inclusion Criteria
- Adult patients scheduled to undergo right heart catheterization at the George Washington University Hospital
Exclusion Criteria
- Patients with known or suspected right-to-left bi-directional or transient right-to-left shunts or pulmonary arteriovenous malformations, previously documented moderate to severe tricuspid regurgitation or moderate to severe pulmonary regurgitation, evidence of right ventricular hypokinesis, or prior adverse reaction to Definity or hypersensitivity to perflutren
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description 2D doppler echo with Definity solution 2D doppler echo with Definity solution Study subjects will already be scheduled for right heart catheterization to diagnose pulmonary hypertension. Prior to the catheterization, each subject will have a 2D doppler echocardiogram with Definity solution as well.
- Primary Outcome Measures
Name Time Method Measure Pulmonary Vascular Resistance using 2D Doppler Echocardiogram w/Definity Solution Two Years Correlation coefficients between the technique above the the gold standard right heart catheterization measures of pulmonary vascular resistance.
- Secondary Outcome Measures
Name Time Method