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Aquired von-Willebrand-Syndrome in Pediatric Cardiac Surgery

Conditions
D68.01
Registration Number
DRKS00014723
Lead Sponsor
niversitätsklinikum Tübingen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
66
Inclusion Criteria

Necessity of Cardiac Surgery or surgery of the great Arteries

Exclusion Criteria

Surgical bleeding with the need of Reoperation (e.g. patch rupture)
Innate von Willebrand Syndrome

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Incidence of AVWS (aquired von Willebrand syndrome).<br>Each blood sample (4 in total / patient) will be tested for AVWS using multimer analysis. For each time point (pre-, intra- and postoperative), the incidence of AVWS will be regarded and reported separately.
Secondary Outcome Measures
NameTimeMethod
Factors influencing the development of AVWS (aquired von Willebrand syndrome)<br>For each time point of blood collection (pre-, intra- and postoperative), the incidence of AVWS will be regarded separately and correlated with the corresponding echogradients / heart defects. In addition, the HLM times are evaluated.
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