NCT01678742已完成不适用
Effects of Jeju Red Horsehead Fish-based, High Protein Diet on Satiety and Incretin Hormones in Diabetes Patients
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Difference in the incremental area under the curve (iAUC) for peptide YY (PYY) after food ingestion between high-protein and standard diet groups
研究概览
简要总结
The aim of our study is to investigate the effects of high-protein diet on satiety and incretin hormones in patients with diabetes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diabetes mellitus
- •Subjects signed a written informed consent form
排除标准
- •Liver cirrhosis
- •Chronic renal disease (serum creatinine > 2mg/dL)
- •Severe congestive heart failure
- •Significant infectious or inflammatory diseases
- •intractable malignant neoplasm
- •Pregnancy
研究组 & 干预措施
Standard diet
Active Comparator
干预措施: Standard diet (Dietary Supplement)
High-protein diet
Experimental
干预措施: High-protein diet (Dietary Supplement)
结局指标
主要结局
Difference in the incremental area under the curve (iAUC) for peptide YY (PYY) after food ingestion between high-protein and standard diet groups
时间窗: 3 hours
Blood samples were drawn before the test meal (time 0) and at 30, 60, 90, 120, and 180 min after the test meal commenced.
次要结局
- Difference in the iAUC for ghrelin after food ingestion between high-protein and standard diet groups(3 hours)
- Difference in the iAUC for glucagon-like peptide 1 (GLP-1) after food ingestion between high-protein and standard diet groups(3 hours)
- Difference in the iAUC for glucose-dependent insulinotropic polypeptide (GIP) after food ingestion between high-protein and standard diet groups(3 hours)
- Difference in the iAUC for cholecystokinin (CCK) after food ingestion between high-protein and standard diet groups(3 hours)
研究者
Gwanpyo Koh
Associate professor
Jeju National University Hospital
研究点 (2)
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