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Clinical Trials/NCT03073252
NCT03073252
Completed
Not Applicable

The Acute Effect of Egg-Based High Protein Meal on Hypertensive Response to Exercise

Purdue University1 site in 1 country31 target enrollmentJanuary 1, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Blood Pressure
Sponsor
Purdue University
Enrollment
31
Locations
1
Primary Endpoint
Blood Pressure Changes
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

The primary purpose of this study is to explore the effect of high versus normal egg-based protein meals on acute exercise-induced elevated blood pressure.

Detailed Description

This study is designed to assess BP changes during and post- exercise after consumption of a test breakfast. The design consists of three visits. The first visit will assess each participants aerobic exercise capacity (VO2 max). Visit 2 and 3 will be clinical testing days where the subject will consume either the 13g or 30g protein breakfast in a randomized cross-over manner and perform the exercise intervention. BP changes will be monitored before and after breakfast consumption, during the exercise intervention,

Registry
clinicaltrials.gov
Start Date
January 1, 2017
End Date
June 30, 2017
Last Updated
8 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Wayne Campbell

Principal Investigator

Purdue University

Eligibility Criteria

Inclusion Criteria

  • Pre-hypertensive (systolic, 120-139 mm Hg; diastolic, 80-89 mm Hg
  • Body weight \<300 lb (136 kg)
  • BMI between 20 and 34.9 kg/m2
  • Fasting plasma glucose \<6.1 mmol/L,
  • total cholesterol \<6.7 mmol/L
  • LDL cholesterol \<4.1 mmol/L
  • TG \<4.5 mmol/L
  • No pre-existing or history of cardiovascular, renal or liver disease
  • Not currently or previously (past 6 mo) consuming a weight-loss diet or other special/non-balanced diets
  • No weight loss/gain (±4.5 kg) within the past 6 mo

Exclusion Criteria

  • Hypertensive
  • Body weight ≥ 300 lb
  • BMI \<20 or \>35 kg/m2
  • Pregnant or planning pregnancy
  • Unwilling to consume study foods and beverages
  • Fasting plasma glucose ≥6.1 mmol/L
  • Total cholesterol ≥6.7 mmol/L
  • LDL cholesterol ≥4.1 mmol/L
  • TG ≥4.5 mmol/L
  • acute illness

Outcomes

Primary Outcomes

Blood Pressure Changes

Time Frame: 6hr testing

Changes from Baseline to Post Systolic Blood Pressure during 30 minute exercise session

Secondary Outcomes

  • Vasoactive Molecules(6 hrs)

Study Sites (1)

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